Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Cardiovascular effects of testosterone: implications of the Áœmale Cardiovascular effects of testosterone: implications of the Áœmale menopauseÁ«? K S Channer1 and T H Jones2. 1Royal Hallamshire Hospital, Sheffield, UK Study Shows Measurable Drop in Testosterone in Women Approaching The data showed that by the time women reached menopause there had been a significant decline in total testosterone, free testosterone, DHT, Personal Health; A Tad of Testosterone Adds Zest to Menopause And when a woman's ovarian function declines in the years before and during natural menopause, so does the amount of testosterone she produces. Amazon.ca: Testosterone: How Testosterone Stops the Male Menopause Amazon.ca: Testosterone: How Testosterone Stops the Male Menopause: Books: Eugene Shippen by Eugene Shippen. Testosterone replacement therapy: beating the male menopause Testosterone replacement therapy: beating the male menopause. Written by Colin Brennan, medical journalist When Reg Eagle was told he had an abnormally low Blood test for testosterone offers menopause early warning hope Blood test for testosterone offers menopause early warning hope. (Menopause).(Brief Article) from Chemistry and Industry in Technology provided by Find Future Medicine - Women's Health - 3(6):663 - Full Text Emerging role of testosterone in menopause. Woraluk Somboonporn. Khon Kaen University, Department of Obstetrics and Gynecology, Faculty of Medicine, Local News - Testosterone Patch Could Increase Sex Drive During Testosterone Patch Could Increase Sex Drive During Menopause nationwide on a patch that would replace the testosterone a woman loses during menopause. IngentaConnect The use of testosterone after menopause The use of testosterone after menopause. Author: Davis S.R.1. Source: Journal of the British Menopause Society, Volume 10, Number 2, June 2004 , pp. Estrogen and Menopause Testosterone and Andropause - Antiaging Atlanta While menopause comes on rather abruptly, the symptoms of Andropause tend to . Estrogen (estradiol) is actually made from testosterone in the cells of Testosterone may improve women's sex lives after menopause The addition of testosterone to hormone therapy in women after menopause enhances their sexual function. However, it may also reduce HDL cholesterol (the. BMJ BestTreatments :: Conditions :: Menopause :: Testosterone Testosterone can also be used to treat symptoms of the menopause. Doctors don't often prescribe it, but they may do if a woman is worried about her loss of Menopause and Testosterone Discover how the so-called 'male' hormone-testosterone can provide relief from the symptoms of menopause, and prevent osteoporosis, as well as increase Testosterone, Women, and Menopause - Women's Health Information about the use of testosterone in women, from your About.com Guide. How testosterone may affect your menopausal symptoms - H01 Experiencing symptoms of menopause? Find out how taking testosterone may help with your menopausal symptoms. Discovery Health :: Testosterone: A Breakthrough for Menopausal Women Dr. Rako's book, "The Hormone of Desire: The Truth About Sexuality, Menopause and Testosterone," is one of a growing wave of publications heralding the The Menopause Clinics of America As the ovaries begin to shut down during menopause, testosterone production is dramatically reduced. Women who do not respond to combined Testosterone Use in Menopause This menopausal woman used hormone therapy consisting of esterified estrogens and methyltestosterone and perineal testosterone, but the topical therapy was MENOPAUSE ONLINE - Androgens, testosterone, Progestins, Progesterone Prior to menopause androgens, mostly testosterone, are produced by the ovaries and adrenal glands. Androgens are important for maintaining bone density and |
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