Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Welcome to the Australasian Menopause Society Australian Capital Territory · Switzerland · Thailand · Philippines · Singapore. © 2008 Australasian Menopause Society | Email Webmaster | Privacy Policy. The International Menopause Society Calls Upon Health Authorities Digg del.icio.us: The International Menopause Society Del.icio.us Newsvine: The International Menopause Society Calls Upon Health Authorities PS Recommendations for estrogen and progestogen use in peri- and Menopause: The Journal of The North American Menopause Society. Vol. 11, No. 6, pp. 589-600. DOI: 10.1097/01.gme.0000145876.76178.dc International Congress Series : Menopause-related definitions First international menopause society definitions 1976 . Geneva, World Health Organization, WHO Technical Report Series 670, Geneva, Switzerland (1981). Women's Mental Health - Keynote Speakers Prof Anita Riecher-Rössler Switzerland . a member of Monash University Council and is the immediate past President of the Australasian Menopause Society. The Journal of The North American Menopause Society The Journal of The North American Menopause Society . Spain, Sri Lanka, Gudan, Suriname, Sualbond And Jan Mayen Islands, Swaziland, Sweden, Switzerland ISI Highly Cited Researchers Version 1.1 II International Symposium of the Portuguese Menopause Society, "Menopause: Hormones and Cancer", 17-17 March, 2001, Lysbon, Portugal, in press. Num. Reg. Európai Menopausa Szervezetek Schanzeneckstraße 1 3012 Bern, Switzerland Phone: +41.31.300.1158 Fax: +41.31.300.1417 E-mail: martin.birkhaeuser@insel.ch. Turkish Menopause Society THE INTERNATIONAL MENOPAUSE SOCIETY The International Menopause Society. ⢠Established in 1978. ⢠Registered as a non-profit organization in Geneva,. Switzerland Society of General Internal Medicine 27th Annual Meeting Geneva, Switzerland: World Health Organization; 1999. Abstract; North American Menopause Society. The role of isoflavones in menopausal health: Sugoo.com- International business portal :: Exhibitions It is hoped the Australasian Menopause Society will help bring together these people, be they doctors, nurses, paramedical or community workers who feel The International Menopause Society Calls Upon Health Authorities The International Menopause Society Calls Upon Health Authorities For Re-Evaluation Of Official Guidelines. October 19th, 2007 | by admin | EMAS: European Menopause and Andropause Society Switzerland. Telephone:, +41 22 908 04 82. Fax:, +41 732 26 07 The European Menopause and Andropause Society (EMAS) was founded to promote the study of EMAS: European Menopause and Andropause Society Swiss Menopause Society Frau Dr. Med Christine Bodmer-Hindermann CH-4031 Bern/Switzerland Phone: +41 31 381 68 00 Fax: +41 31 381 68 01 International Menopause Society - Home Welcome to the website of the International Menopause Society (IMS). Society is the registered address of the Society's lawyer in Geneva, Switzerland. International Menopause Society - Society News Briefing for the European media in early October in Zurich, Switzerland. . International Menopause Society, Mrs Jean Wright, IMS Executive Director, Welcome to the Australasian Menopause Society WHO Technical Report Series 866, Geneva, Switzerland, 1994. © 2007 Australasian Menopause Society | Email Webmaster | Privacy Policy. |
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