Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Is This Perimenopause? A look at the signs and symptoms of perimenopause with suggestions for relief. Hot flashes and/or night sweats are common signs of perimenopause. Perimenopausal Signs and Symptoms A simple look at the most common signs and symptoms of perimenopause with resources for more information about perimenopause and menopause. What is Perimenopause? - WebMD What Are the Signs of Perimenopause? You will know you are transitioning into menopause when you begin experiencing some or all of the following symptoms: Sign and Symptom of Perimenopause - Perimenopause: Are You in its Perimenopause, women, menopause, anovulatory, hormones, ovaries, estrogen, progesterone, androgen, heart disease, osteoporosis, colon cancer, Perimenopause: Signs of Change Irregular periods, breast tenderness, worsening PMS, and diminished libido can all be signs that you're experiencing perimenopause. Signs which may be associated with (peri)menopause Personal decisions concerning symptoms which may "just" be signs of (peri)menopause must be made in consultation with a health care provider. Signs and Symptoms of Perimenopause - Associated Content Check out Signs and Symptoms of Perimenopause - Submitted by LL Ford at Associated Content. Women's health: Signs of Perimenopause - Menopause and Treatment Hot flashes and night sweats are very common sign of perimenopause menopause, menopause. Night sweat, hot flushes, in the night. Perimenopause symptoms In fact, most women will experience menopause symptoms and the signs of menopause years before their periods actually stop. For most women, perimenopause or Perimenopause - CNN.com When perimenopause starts and how long it lasts varies. You'll probably notice signs of impending menopause, such as menstrual irregularities, What are signs of perimenopause? - Yahoo! Answers I have a 9 month old baby and now when she is waki Menopause Symptoms, What is it? When does it happen? Power Surge What should I expect as I go through perimenopause? Additional Reading: The 34 Signs/Symptoms of Menopause. Some women have symptoms during this time that 35 Symptoms of Menopause This list of common symptoms that occur during perimenopause and menopause was developed SOME OF THE 35 SYMPTOMS MAY ALSO BE SIGNS OF THE FOLLOWING: Get Ready: The Signs of Perimenopause Get Ready: The Signs of Perimenopause. Last Updated: May 1, 2003. Changing hormone levels can cause a variety of symptoms that may last from a few months to Perimenopause symptoms and understanding signs of hormonal change Symptoms and signs of perimenopause including help in understanding and coping with hormonal change in women. signs of menopause Signs 1-14 are the major, most common signs of peri-menopause and menopause; the signs that a woman most often consults a physician or other health care Daily Record MorrisLife - Mood swings could be a sign of perimenopause Mood swings could be a sign of perimenopause. By Jennifer Agnello, Special to the Daily Record. Q. I am in my mid-40s and have been experiencing mood swings Hotflash! News - Common Perimenopause Signs and Symptoms Common Perimenopause Signs & Symptoms occur during a time where hormone levels widely fluctuate and render the hallmark traits such as hot flashes, What are the signs of perimenopause in terms of periods? - Blurtit What are the signs of perimenopause in terms of periods? |
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