Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Bleeding won't stop. - Menopause - MedHelp This is a discussion on MedHelp about Bleeding won't stop. since I'm 46 I'm probably starting early menopause, she said heavy prolonged bleedingBleeding The Menopause Web Reference Relationship between Menopause, Menopausal Blues and Depression . Heavy and/or prolonged uterine bleeding can result in anemia which in and of itself can Abnormal Uterine Bleeding: A Management Algorithm However, if the bleeding is prolonged (>7 days) or does not respond to hormonal therapy as Menorrhagia and abnormal bleeding before the menopause. Menopause Message Boards and Menopause Forums -- Power Surge Prolonged bleeding, Prolonged bleeding. Options V . and that came back "normal", which doesn't say a lot since I'm in peri and not yet in menopause). Changes to Expect - Yahoo! Health Some women continue to menstruate normally until the onset of menopause and then Heavy and prolonged bleeding arise when a longer than normal release of WOMENS-HEALTH Messages for February, 1999: Prempro & prolonged Prempro & prolonged bleeding. From: Sue (anonymous@obgyn.net) I went through menopause with no symptoms other than irregular periods. prolonged menstral bleeding perimenopause >> Medical Questions Hello! I am 47 years old woman and for the last 4 months I have experienced prolonged menstrual bleeding, with occasional cramping. MedlinePlus Medical Encyclopedia: Menstrual periods - heavy Your periods have been heavy or prolonged for three or more cycles, You have bleeding after menopause. You have bleeding or spotting between periods. Answer to a newbie's questions on perimenopause I really experience no other symptoms of menopause with the exception of slight problem in perimenopause has been heavy-frequent-and-prolonged bleeding. Irregular periods in perimenopause Bleeding, heavy and prolonged bleeding, can happen without any warning bloat or mood still it is definitely "irregular" to have post menopause bleeding. NFPS-7815 S-T CHART PRE-MENOPAUSE CYCLIC CHANGES DURING THE PRE-MENOPAUSE. It is important that women are aware of the Sudden brief or more prolonged episodes of bleeding or flooding Symptoms Of Menopause - Irregular Bleeding A common reason for the late periods and prolonged bleeding is due to 'anovulation' of Life and Long-Term Health with Early Menopause Detection Buy Now UpToDate Patient information: Abnormal uterine bleeding Causes of abnormal bleeding during menopause include: prolonged or excessive bleeding that is due to hormonal changes and that is unresponsive to other Is This Menopause? | Hystersisters Article See your doctor if your bleeding is extremely heavy and prolonged and occurs between periods or during intercourse or begins after menopause (you haven't Treatment of Constant Vaginal Bleeding Close to Menopause - I01 Prior to menopause I think it is better to use a low dose oral contraceptive such as . With both the prolapse and the prolonged uterine bleeding problem, The menopause - (1) The menopause and its implications The end of cyclic bleeding - the menopause - is thus only one event in a whole A good general rule is that if the patient reports prolonged bleeding or Menorrhagia (heavy menstrual bleeding) - CNN.com Older women approaching menopause often experience hormonal imbalance that can cause Excessive or prolonged menstrual bleeding can lead to other medical eMedicine - Dysfunctional Uterine Bleeding : Article by Millie Prolonged uterine bleeding suggests the epithelial lining of the cavity has become denuded over time. In this setting, a progestin is unlikely to control Learn more about prolonged and heavy perimenopausal bleeding - I01 Woman's Diagnostic Cyber article about prolonged and heavy perimenopausal menstrual bleeding Treatment of Constant Vaginal Bleeding Close to Menopause |
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