Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Early Menopause, Premature Menopause Because of the nature of early or premature menopause the woman will experience another level of emotional reaction to her situation than someone who comes Premature Menopause Myths - DrDonnica.com - The First Name in Dr. Donnica discusses what premature menopause is and what is available to treat it today. Premature Menopause: When āThe Changeā Comes Too Early - DrDonnica Symptoms of premature menopause are generally the same as regular menopause, except that the sufferer usually experiences night sweats and physical and Premature menopause - WebMD Treatment for breast cancer can result in infertility of premature menopause. WebMD helps you understand how treatment will affect you. Breast Cancer and Infertility and Premature Menopause Details premature menopause (PMM), termed premature ovarian failure. ivf-infertility.com | Premature menopause (PMM) Amazon.com: The Premature Menopause Book:: When The "change Of Life" Comes Too Early: Books: Kathryn Petras by Kathryn Petras. Amazon.com: The Premature Menopause Book:: When The "change Of Registered UK charity organization supporting those affected by premature menopause. Information regarding menopause stages and treatments is available. Welcome To The Daisy Network Premature ovarian failure (POF) is when a woman's ovaries stop working before she is 40. POF used to be called premature menopause. MedlinePlus: Premature Ovarian Failure premature menopause. Font Size. A · A · A. failure of cyclic ovarian function before age 40. Syn: premature ovarian failure What is premature menopause? Find the definition for premature This Yale-New Haven HealthLINK (December 2002) focuses on premature menopause caused by adjuvant chemotherapy or hormone therapy in women with breast Premature menopause side effect of breast cancer treatment Women who survived cancer during childhood are at risk of premature menopause, researchers report Tuesday. USATODAY.com - Cancer, premature menopause linked Early menopause ā The North American Menopause Society, devoted to promoting women's health through understanding of early menopause symptoms, premature Early Menopause.com A woman with premature ovarian failure, or premature menopause, may still have follicles, but there may be a depletion or dysfunction of these. Premature Ovarian Failure: American Pregnancy Association Premature menopause is when menopause occurs before age 40. Symptoms include night sweats, hot flashes, mood swings, decreased sex drive. Premature Menopause Causes, Symptoms, Diagnosis and Treatment on The most common misperception is that POF (premature ovarian failure) just isnāta big deal. Upon hearing of this condition, many who are not affected react Premature Ovarian Failure, Surgical or Medical Menopause For women going through early menopause or premature ovarian failure (POF) whether naturally, surgically or due to cancer treatments. |
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