Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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OBGYN.net The Significance of Bleeding after the Menopause Banter approach menopause is one where the periods become lighter, shorter in duration, In conclusion, women who are experiencing post-menopausal bleeding Evaluation and treatment of post-menopausal bleeding (If itÁ™s been less than a year since your last period, you are not yet post-menopausal. For information on irregular bleeding during the years leading up to Post menopausal Á” what is post menopause? Exactly what is menopause, and what does Áœpost-menopauseÁ« mean? Literally, the term means after the menopause or the stopping of periods. The Stages of Menopause Post-menopause begins with your final period and lasts the rest of your life. While the signs of menopause taper off over a year or two, Post Menopause Q & A - Reader Questions on Post Menopause Once your menstrual periods stop for good (at least a full year), it is extremely unlikely that you can become pregnant. How long does post menopause last? Post-Menopausal Bleeding on MedicineNet.com Post-Menopausal Bleeding Not Normal. Nine Months After Periods Cease, Bleeding May Signify Cancer. By Jeanie Lerche Davis WebMD Feature What Is? You may produce enough estrogen on your own to get periods on occasion -- even after having been tested at post-menopausal levels. WOMENS-HEALTH Messages for April, 2003: Post Menopausal period Post Menopausal period. From: Donna (anonymous@obgyn.net) Next in thread: Hector Nemirovsky M.D.: "Re: Post Menopausal period"; Reply: Hector Nemirovsky New clinical guideline on post-menopausal bleeding issued NEW CLINICAL GUIDELINE ON POST-MENOPAUSAL BLEEDING ISSUED FOLLOWING INCREASE IN Á˜post menopausalÁ™ bleeding and at what stage after a womanÁ™s last period Post Menopause : Life After the Change For a woman to be considered in post-menopause, she would be void of a menstrual period for a minimum of one year. Although as women age they may miss a The post menopause stage Post menopause is the period when a woman does not have her monthly periods The third and final stage in women's life cycle is post menopause period. Maturitas : HRT and heart disease: problems and prospects The hormonal therapy was most often initiated in the direct peri-menopausal or post-menopausal period for the relief of menopausal symptoms. Are You In Out Or Post Menopause - AOL Body Are You In, Out or Post-Menopause? - We read and hear so much about menopause that There is a period of transition from regular periods to menopause, Menopause - Wikipedia, the free encyclopedia When she reaches that point, she is one year into post-menopause. The reason for this delay in declaring a woman post-menopausal is because periods become Post Menopause Article If a woman has not had a period for twelve months, then she is considered to be in the post menopause stage of life. Many of the symptoms that made life Post Menopause Symptoms Article Perimenopause is an approximate four year period of time when women are experiencing the most obvious symptoms. A woman is officially in post menopause when A Comparison Of Mental Health Status During Menopause And Post All mean scores except social dysfunction were observed slightly higher for post-menopausal women compared to women belonging to menopausal period. Symptoms, Their Causes & Cures Post-Menopausal Bleeding Post-Menopausal Bleeding This doesn't mean, however, that your period suddenly stops. It's very common for women going through menopause to have BBC - Health - Ask the doctor - Post-menopausal bleeding While it could simply be that you're still having a few periods, there are more worrying reasons for bleeding after the menopause which need to be ruled out |
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