Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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WOMENS-HEALTH Messages for March, 2001: Post Menopausal Breast I'm 58 years old and post menopausal for 7 years. Six months ago, I started getting breast pain on and off in either breast. Shortly thereafter, I started Frequently Asked Questions Answer: In pre-menopausal women, the best time to do breast self-examination is generally a week after your menses. In post-menopausal women, Inflammatory Breast Cancer usually appears with a swollen breast Breast pain (from a constant ache to stabbing pains) in each of three menopausal periods of life: premenopausal, perimenopausal, and postmenopausal. Symptoms, Their Causes & Cures Post-Menopausal Bleeding Post-Menopausal Bleeding You have any bleeding at all after menopauseâ”light or heavy. * You are on hormone replacement therapy, and your bleeding is not Menopause Message Boards and Menopause Forums -- Power Surge My right breast is always a little sore I'm 2 years post menopause. . A warm feeling in the breast * Itching of the breast * Pain OBGYN.net Breast Care FAQ - Breast Symptoms A: Breast pain can be one of the effects of early pregnancy. Leaking can occur in some women. .. I am 62 post menopausal who hasn't had a mammogram. Breast Pain Breast pain is a common complaint and a source of great distress for many women Post-menopausal women on estrogen supplements may find a relief in their Older women's health : Directgov - Over 50s Health issues for women over 50 such as menopause, breast cancer, cervical cancer, Other symptoms include persistent breast pain, nipple discharge, Persistent Pelvic Pain Post-Menopausal - Urogynecology - MedHelp Persistent Pelvic Pain Post-Menopausal. Jul 21 by Kathyapp. Tags: persistent, pelvic, pain, UroGynecology, Breast - premenstrual tenderness and swelling Imaginis - Breast Pain Breast pain (mastalgia) is the most common breast related complaint among The condition may occur in both pre-menopausal and post-menopausal women and Fibrocystic breast disease, breast pain & bra wearing One study found that lack of breastfeeding was a risk factor for having post-menopausal breast pain and fibrocystic changes. Breastfeeding definitely lowers |
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