Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Perimenopause & Anxiety Moving through perimenopause can exacerbate or create symptoms such as panic, anxiety, depression, and mood swings. Estrogen has a tranquilizing effect on What is Perimenopause? - WebMD Additional treatments available to help with the various symptoms of perimenopause may include antidepressant medications for mood swings. Perimenopause (premenopause) Perimenopause is the phase before menopause actually takes place, when ovarian hormone mood swings, breast tenderness and many other complications. Menopausal Mood Swings Menopausal Mood Swings. Does Perimenopause Cause Mood Changes? A look at how perimenopause and menopause may cause mood swings in some women. Perimenopause naturally: an integrative medicine approach On average, the onset of perimenopause occurs around age 47, with the average . headaches, insomnia and mood swings, were seen in 80% of the women, Bioidentical Hormones & Custom HRT : Perimenopause Symptoms: Mood During perimenopause, cycles usually become irregular and hormone levels fluctuate which can lead to mood swings at unpredictable times. Menopause Mood Swings | Perimenopause Mood Swings | Treatment Mood Menopause Mood Swings Know the difference between feeling occasionally blue to extreme hormonal mood swings caused by menopause or perimenopause sypmtoms. Menopause and Natural Support for Mood Swings Natural Support for Mood Swings. Depression and other mood disorders are common that as many as 80% of perimenopausal women develop mood disturbances. DailyStrength.org - Perimenopause mood swings I exercise, try to eat ok, take some vitamins, but I still have some bad mood swings. I am just running hot and cold. Everyone has problems in their life. Menopause Discussions at DailyStrength: Perimenopause mood swings Discussions · DailyStrength.org - Perimenopause mood swings slpa here-yes i have been battling my mood disorders plus anxiety and past things have come Canadian Living : Health : Prevention : Hot flashes? Wild mood swings? Hot flashes? Wild mood swings? Explore natural ways to breeze through perimenopausal symptoms. By Dahlia Reich. Causes and signs Mood Swings But many women do experience mood swings during perimenopause. Happy highs that turn into teary-eyed lows. Cheerful times followed by crabby days. Mood perimenopause symptoms Almost every woman will have certain level of mood swings during perimenopause. This can become a big problem when the intensity and frequency of mood Daily Record MorrisLife - Mood swings could be a sign of perimenopause Mood swings could be a sign of perimenopause. By Jennifer Agnello, Special to the Daily Record. Q. I am in my mid-40s and have been experiencing mood swings Mood swings and irritability Mood swings and irritability have an emotional aspect as well. Perimenopause is a time when many women find their true voices. That's a good and natural Symptoms of Perimenopause Although each woman experiences perimenopause (the period leading up to Again, mood swings are not a given, as researchers report that many women report Perimenopause Mood Swings, Peri Menopause Mood Swing Did you know that Perimenopause mood swings are something that most women will face? If you are approaching 40, it is time to take note of these times when Do you suffer from perimenopause depression, anxiety, anger, and Ideally, women with perimenopause depression, anxiety, anger and mood swings should exercise a minimum of 30 minutes three to four days each week. Perimenopause - CNN.com Mood changes. Some women experience mood swings, irritability or depression during perimenopause, but the cause of these symptoms may be sleep disruption or |
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