Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Do you suffer from perimenopause depression, anxiety, anger, and In addition to the physical changes a women experiences in perimenopause, the emotional issues of depression, anxiety, anger and mood swing issues often go IngentaConnect Mood and perimenopause Mood and perimenopause. Authors: Alexander J.; Thompson D.; Dennerstein L.; Bachman G.; Bachman G. Source: Journal of Psychosomatic Research, Volume 55, IngentaConnect Mood and perimenopause Mood and perimenopause. Author: Dennersjein L. Source: Journal of Psychosomatic Research, Volume 55, Number 2, August 2003 , pp. 129-129(1) Estrogen Lifts Mood in Perimenopause | National Institutes of Estrogen Lifts Mood in Perimenopause from National Institutes of Health in Health provided free by Find Articles. Menopause Discussions at DailyStrength: Perimenopause mood swings I've always had mood issues at times, but now it's ridiculous. I think my husband is at the end of his rope with me and I just can't even explain it to him. Mood perimenopause symptoms Almost every woman will have certain level of moods wings during perimenopause. This symptom can become a big problem when the intensity and frequency of Bioidentical Hormones & Custom HRT : Perimenopause Symptoms: Mood Find information on Custom HRT, Symptoms of Menopause and Male Menopause. Also if you are looking for information on bioidentical hormones and perimenopause perimenopause mood and energy management program Comprehensive nutritional and longeviety principals for effective mood and energy management during peri-menopause. peri-menopause Perimenopause Mood and Energy Management Program - takes you systematically through a six month program designed to shift your health and self-care focus to Perimenopause-Related Mood and Behavioral Disorders - Full Text History within the last one year of at least one month with perimenopause-related mood or behavioral disturbances of at least moderate severity - that is, NIH News Release-Estrogen Lifts Mood in Perimenopause - 08/28/2000 Estrogen levels, body thermostats and mood often fluctuate in the perimenopause. But only a minority of women become clinically depressed. Estrogen Lifts Mood In Perimenopause Women who suffer depression as they enter the early stages of menopause (perimenopause) may find estrogen to be an alternative to traditional Institute for Mental Health Research - Current Newsletter Many women in the transition period before menopause, known as "perimenopause," experience mood symptoms. Whether there is an actual increase in depressed Perimenopause Mood Swings, Peri Menopause Mood Swing Did you know that Perimenopause mood swings are something that most women will face? If you are approaching 40, it is time to take note of these times when Topics-Mood Disorders and Menopause The transition to menopause or perimenopause represents the passage from on the use of estrogen to improve mood and cognition in perimenopausal women. Perimenopause-Related Mood Disorders - Evaluation, Treatment and The National Institute of Mental Health is actively seeking patients with Perimenopause-Related Mood Disorders to receive free evaluation and/or treatment Does Perimenopause Cause Mood Changes? A look at mood changes during perimenopause and the role of hormones. menopause and mood Menopause and Mood (revised 9/2006). (See also, if needed, menopause and bipolar disorder). Menopause (primarily "perimenopause", the phase up to 10 years |
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