Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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The perimenopause and contraception. The perimenopause and contraception. Shaaban MM. Department of Obstetrics and Gynecology, School of Medicine, Assiut University, Egypt. Contraception in the perimenopause. Contraception in the perimenopause. Sparrow M. PIP: Most clinicians advise women to continue using contraception for 12 months after menstruation has ceased Oral Contraceptive Use During the Perimenopausal Years - October Few guidelines exist for the use of estrogen, particularly low-dose oral contraceptives, during the perimenopausal years. Use of low-dose oral contraceptive Contraception in the perimenopause This article describes some of the theoretical advantages and disadvantages of various methods of contraception for perimenopausal women. IngentaConnect Contraception during perimenopause Keywords: Perimenopause; Contraception; Oral contraceptives; IUDs; Tubal ligation; Barrier contraceptive methods; Hormonal injectables and implants IngentaConnect The perimenopause and contraception Keywords: Perimenopause; Premenopause; Contraception; Climacteric symptoms; Combined contraceptive pill; Low-dose combined pills; Cardiovascular risks; Contraception Online Slides - perimenopause, contraception As such, perimenopausal women should be counseled about the risks of unintended pregnancy and options for contraception. Women who experience perimenopausal Contraception Online: Contraception and Reproductive Health Info Contraception for Women in the Perimenopause. The number of US women entering the perimenopause is at an all-time high. A growing number are opting to delay Perimenopausal Contraception (FACT) To be reviewed not later than 31 October 2004 PERIMENOPAUSAL CONTRACEPTION Dr S Brechin and Dr A Gebbie Introduction The perimenopause or climacteric is the BioMed Central | Full text | Perimenopausal contraception in Epidemiologic research has shown that perimenopausal contraception is an important medical issue, because women during the perimenopause still need 1472-6955-6-1 1472-6955 Research article Perimenopausal Epidemiologic research has shown that perimenopausal contraception is an . Contraception in the perimenopause Gebbie A J Br Menopause Soc 2003 9 123 8 Contraceptive Options for Perimenopausal Women Surgical sterilization remains the most popular form of contraception among perimenopausal-aged couples. Natural family planning techniques are safe and Oral Contraceptives for Perimenopausal Women Some good news though is that, as long as she is healthy and does not smoke, oral contraceptive use in perimenopausal women does not increase the risk of FHA Article Summary - The perimenopause: contraception advice (Jul-2007); Perimenopausal contraception in Turkish women: A cross-sectional study. (2007); Specialist contraceptive counselling and provision after Contraception still necessary in perimenopause.(Clinical Rounds Contraception still necessary in perimenopause.(Clinical Rounds) from Skin & Allergy News in Health provided by Find Articles. Contraception at the perimenopause ping contraception for women aged over 50 years, using various. methods. Contraception at the. perimenopause. Gillian Penney Contraception : Contraception and treatment in the perimenopause Although there is a reduced frequency of ovulation in perimenopause, contraception is still necessary. Unplanned pregnancies and induced abortions are Vasomotor Symptoms and Contraception in Perimenopause - Journal Few clinical trial data address contraception or treatment of vasomotor symptoms in perimenopausal women. This six-month Italian trial examined the effects |
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