Study Finds Menopause Symptoms Can Be Predicted

The number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.

Researchers now say they may be able to predict when that clock will wind down.

And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left.

According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason.

Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction.

"If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments."

Others reiterate, however, that the findings should be treated with caution.

"Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life."

According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000.

The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold.

The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause.

The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct.

While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated.

The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40.

SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction

perimenopause back pain
Symptoms of Perimenopause
5, Back Pain Japanese and living in Japan, you probably have no symptoms of perimenopause. and red blotches may appear on your chest, back and arms.

What is perimenopause? Find the definition for perimenopause at WebMD
perimenopause. Pronunciation (perā²i-menā²Å-pawz). Font Size Back To Glossary. WebMD Medical Reference from "Stedman's Medical Dictionary"

Anxiety/perimenopause - Menopause - MedHelp
This is a discussion on MedHelp about Anxiety/perimenopause. The doctor told me that my body was now just getting backBack pain - low

ENDO Messages for July, 2004: D. N. Re: Pain getting worse w
The endo builds up during perimenopause w/ nowhere to go. >centralized and it can cause sciatica pain and low back pain. Sometimes

Like Perimenopause at 34 years of age? - Women's Health - MedHelp
This year, I have had 3 unusual periods (backBack pain - low It sounds hormonal, maybe not perimenopause although some women do have symptoms that start

peri-menopause burning hands feet arms >> Medical Questions
I am 48 and my gyn says in peri- menopause. I have few problems that are bothering me only bleeding when i peepain in labia.. burning while i pee.

168 Climacteric see Perimenopause Clinical Trials
treatment of acute and chronic non-specific low back pain. A sys-. tematic review of randomized trials of Climacteric see Perimenopause. Clinical Trials

What is Perimenopause? - WebMD
WedMD helps you understand the transition into perimenopause. heart attack and stroke. Now it is finding its way back into medicine cabinets.

Menopause and Perimenopause-Overview
What are menopause, perimenopause, and postmenopause?Menopause is the milestone in every woman's Now it is finding its way back into medicine cabinets.

Answers to FAQs and Articles about Perimenopause and early
Answers to your most frequently asked questions FAQs about perimenopause and early I decided to go back on the HRT. I have had numerous symptoms

Perimenopause Support
We are your complete resource for all things relating to Perimenopause. --Select Symptom--, Anxiety, Back Pain, Brain Fog, Breast Pain, Chronic Fatigue

Perimenopause & Back & Neck Pain
PerimenopauseSupport.com is the first site completely devoted to helping women through Perimenopause. Get the latest research, support, information,

InteliHealth:
Perimenopause, in fact, spans a few or many years leading up to menopause. Some feel irritable or are depressed." Back To Top . Low Back Pain

InteliHealth:
Perimenopause, also known as the climacteric, includes the time before menopause Symptoms of menopause or perimenopause include: .. Low Back Pain

Menopause - Wikipedia, the free encyclopedia
Symptoms of perimenopause can begin as early as age 35, although most women become . with hot flashes; joint pain and muscle pain; and depressed mood.

OBGYN.net Menopause & Perimenopause Ask The Expert
Could my back pain and abdominal discomfort be a sign of ovarian cancer or related to In the early perimenopause the ovaries produce enough estrogens.

OBGYN.net Menopause & Perimenopause Ask The Expert, January, 2000
Question: Are fatigue and dizziness symptoms of perimenopause? The next day I had terrible lower back pain and it continued into the next day.

Power Surge Forums > Perimenopause Symptoms for 2 years
I am 46 years old and the Perimenopause Symptoms that I have experienced for fatique, muscle and joint pain, lower back pain, clotting with periods,

Interstitial Cystitis, IC, Hormones, Perimenopause and Menopause
Pressure on pelvic veins can cause painful varicose veins, pelvic and leg pain. Perimenopause is a time to keep back muscles strong, use good support while


perimenopause back pain
menopause hormone fluctuations lightheaded
perimenopause hormone replacement therapy
menopause hrt
menopause relief weight gain