Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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OBGYN.net Menopause & Perimenopause Ask The Expert But many Americans consider the perimenopausal period (the climacteric transition) also menopause. Perimenopausal women have (irregular) periods. OBGYN.net Menopause & Perimenopause Ask The Expert March, 2000 But without any complaint, why worry about remedies? 43 is not too young to start with perimenopause. This period will stay for 4 years (mean) and sometimes Irregular periods in perimenopause Again I attributed this to perimenopause and started reading every book on menopause in the public library. I still had fairly regular periods about every Is This Perimenopause? Perimenopause is the ten to fifteen years before menopause occurs. Menopause officially occurs when you have not had a period for one year. Women's Health and Fitness During Menopause - Perimenopause and Perimenopause and Phantom Periods. As women approach menopause and experience symptoms of perimenopause, itÁ™s not unusual to have ÁœphantomÁ« periods. Vitamins for Perimenopause - Irregular Perimenopause Period - Mitamins Information related to Irregular Perimenopause Period and nutritional formulas to support Perimenopause. Quality custom made vitamin and supplement formulas Perimenopause Best Syndication,women in their 40s typically go into the perimenopause period. because estrogen levels begin to drop, women may experience thinning hair Before the Change : Taking Charge of Your Perimenopause With this essential do-it-yourself program, you can say good-bye to hormone havoc and sail through your perimenopause, the period of about ten years leading Changes in Urinary Excretion of Type-I Collagen Cross-Linked C However, there are few reports on the change in these bone resorption markers during the perimenopausal transition period with the exception of those by Learn the basics about menopause: what is it and how it's treated The perimenopausal period begins on the average at about 47 1/2 years. That is the time at which many women will note some menstrual irregularity. Perimenopause - CNN.com Perimenopause encompasses the years leading up to menopause Á” anywhere from two to eight years Á” plus the first year after your final period. Perimenopause But menopause itself is only one day--the day you havenÁ™t had a period for 12 months in a row. During perimenopause, your ovaries start to shut down, Irregular Menstrual Periods in Perimenopause and Menopause Irregular periods are a common symptom of perimenopause, the time before menopause itself. You may experience a change in the menstrual cycle, Irregular periods - understanding the menstrual cycle Women entering perimenopause often have irregular periods due to an imbalance of Click here to learn more about irregular periods in perimenopause. Perimenopause Symptoms - Pycnogenol and Black Cohosh Information The term ÁœperimenopauseÁ« should include the period immediately prior to the menopause (when the endocrinological, biological, and clinical features of Perimenopause (premenopause) Some clinicians maintain that perimenopause can last for as long as 5 to 15 years, while others refer to perimenopause as that period which is a 3 to 4 year Perimenopausal and menopausal bleeding Regular periods are the result of a precise hormone balance causing regular ovulation. In perimenopause changes in hormone levels interfere with ovulation. Perimenopause Perimenopause is defined as the TRANSITIONAL period from normal menstrual periods to no periods at all. The transition can, and usually does, take up to ten Symptoms of Perimenopause Although each woman experiences perimenopause (the period leading up to menopause) and menopause differently, you may experience one, some, all, |
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