Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Indiwo.com > For the Indian woman > All About Perimenopause > Gynaec Are you between 35 and 40 and are worried about irregular bleeding? This is one of most common symptoms of perimenopause, or the onset, to the preparation Menopause Discussions at DailyStrength: Irregular bleeding during I'm 49 years old and am pret-ty sure I'm in the throes of perimenopause. What's with this irregular, nonspecific bleeding pattern? Heavy deluge of flooding Healthy Viewpoints For perimenopausal women with abnormal uterine bleeding, please see your healthcare provider if you are experiencing irregular bleeding. Learn more about prolonged and heavy perimenopausal bleeding - I01 Polyps probably account for about 10% of perimenopausal bleeding problems (1). Since most of the bleeding problems stem from irregular or absent 40&better - Articles > Life Changes, Changing Lives > Premenopause In perimenopause changes in hormone levels interfere with ovulation. It is not unusual to have irregular bleeding for up to 6 months before menstrual Abnormal Uterine Bleeding - October 1, 1999 - American Academy of Initial Approach to Abnormal Uterine Bleeding in Perimenopausal Patients up to 40 percent of women have irregular bleeding in the first four to six Menses What the woman sees as a hormone imbalance is not only irregular bleeding, but also the emotional swings and other symptoms of "perimenopause. What can I do about irregular bleeding during perimenopause What can I do about irregular bleeding during perimenopause? from Harvard Womens Health Watch in Health provided by Find Articles. Frequently Asked Questions About Menopause and Perimenopause -What What are the symptoms of perimenopause? Common symptoms include irregular bleeding, hotflashes, night sweats, mood changes, vaginal dryness, decreased Menopause Perimenopause Mature Sexuality Aging HRT Womens Health As you enter the perimenopause, your own cycles may become much more irregular. Often, the interval between bleeding becomes shorter and the bleeding Menopausal Bleeding - Irregular Bleeding During Perimenopause and Irregular Menstruation During Perimenopause. Irregular bleeding is very common in women who are approaching menopause. In fact, it is the prime indicator Symptoms Of Menopause - Irregular Bleeding The unpredictable aspect of the perimenopause can be the most frustrating. Persistent irregular bleeding can be a tip to obtain further evaluation with your Irregular periods in perimenopause "Irregular" periods as feature of perimenopause . two spots to be specific, still it is definitely "irregular" to have post menopause bleeding. Perimenopause Is Heavy, Irregular Bleeding, or Bleeding After Sex Normal During Perimenopause? A look at irregular bleeding during perimenopause. Irregular periods - understanding the menstrual cycle Alternatively, she may have heavy episodes of bleeding every two to three months. Women entering perimenopause often have irregular periods due to an Is Heavy, Irregular Bleeding, or Bleeding After Sex Normal During A. While it's normal to experience irregular bleeding during perimenopause, it's important to understand that not all menstrual problems are caused by Irregular Menstrual Periods in Perimenopause and Menopause Irregular periods are a common symptom of perimenopause, the time before Some doctors use birth control pills to control the irregular bleeding and Perimenopausal and menopausal bleeding Why is bleeding irregular in perimenopause? Regular periods are the result of a precise hormone balance causing regular ovulation. In perimenopause changes |
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