Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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WOMENS-HEALTH Messages for June, 2002: At what age does peri Reply: Joyce: "Re: At what age does peri-menopause start?" Reply: Another: "Re: At what age does peri-menopause start?" Perimenopause - WrongDiagnosis.com Perimenopause information including symptoms, diagnosis, misdiagnosis, treatment, (Source: excerpt from Menopause - Age Page - Health Information: NIA) Menopause Perimenopause Female Age Infertility Menopause is a natural consequence of female aging and can be moderated with medications. Dr. Kustin has extensive experience treated menopausal and Frequently Asked Questions About Menopause and Perimenopause -What Women tend to reach menopause at about the same age that their mother and sisters did, Treatments for perimenopause can include birth control pills, Menopause and Peri-Menopause Perimenopause can begin as early as age thirty, however, the average age is fifty-one. Some of the symptoms associated with perimenopause are as follows: Perimenopause - CNN.com No one test or sign is enough to determine if you've entered perimenopause. Your doctor takes many things into consideration, including your age, WOMENS-HEALTH Messages for June, 2002: Re: At what age does peri Next in thread: M.K.: "Re: At what age does peri-menopause start?" Reply: M.K.: "Re: At what age does peri-menopause start?" Reply: JZS: "Re: At what age The Influence of Age on Symptoms of Perimenopause perimenopause (Holte, 1992). Perimenopausal women. TABLE 5. ANOVA Summaries for Frequency and Severity of. Perimenopausal Symptoms Among Age Groups Reproductive Characteristics and the Age at Inception of the There was some evidence that early age at menarche and short menstrual cycles were associated with an earlier perimenopause. No relation was observed with Reproductive Characteristics and the Age at Inception of the Reproductive Characteristics and Perimenopausal Age 613 .. Estimates of median age at perimenopause for various combinations of risk factors taken Getting pregnant during perimenopause at age 45 >> Medical I am 45 years old. The doctor said I am at the end of my perimenopause and it would take a miracle to get pregant. I desperately want a second child. Menopause - Wikipedia, the free encyclopedia Symptoms of perimenopause can begin as early as age 35, although most women become aware of them about 10 years later than this. Perimenopause can last for Baptist Health Library - Detail And, with the average age of menopause being 51 years of age, that starting age for perimenopause could be as young as 41 years old. Oral Contraceptive Use During the Perimenopausal Years - October However, few guidelines exist for estrogen supplementation or hormone therapy in the perimenopausal age group. The "perimenopausal decade," which usually Power Surge Forums > The average age for perimenopause is? Although I have not smoked for over 11 years, maybe the damage was already done, maybe it does lower the age of perimenopause? Diagnose-Me: Condition: Perimenopausal Issues On average, the onset of perimenopause occurs around age 47 and the average duration is 4-5 years. It is increasingly seen in women even up to 12-15 years The Facts About Perimenopause and Menopause Perimenopause occurs typically around age forty, but it's normal to begin in your thirties when your menstrual cycle is normal. The onset of perimenopause Understanding the Symptoms of Perimenopause Outward signs may not manifest themselves until closer to age 45. In my mind, the whole decade of the 40s could be considered perimenopause,Á« she added. Perimenopause Remember menopause before the age of 40 is called premature menopause and is rare. However perimenopause can begin before age 40. |
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