Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Osteoporosis Risk Factors, Fractures, Primary or Secondary Osteoporosis: Risk Factors. researched and written by the ProjectAWARE group Late menarche, early menopause, and low endogenous estrogen levels are also Guideline 71 Section 2: Risk factors for osteoporosis Strongest risk factors, Other significant risk factors. Female sex Age > 60 years Family history of osteoporosis. Caucasian origin Early menopause IngentaConnect Risk factors of osteoporosis in Thai women To assess risk factors of osteoporosis, 331 women attending menopause clinic at Chulalongkorn hospital from January-September, 1995 were recruited for the Osteoporosis Risk Assessment for Postmenopausal Women The more risk factors you check, the greater your risk for osteoporosis. (BMD) testing is recommended after menopause for women with risk factors and Patient Education Biological and Medical Risk Factors. Biological Sex - Women have a greater chance of developing osteoporosis. Race - Caucasians and Asians are at greater Risk Factors Women who undergo surgical menopause have an abrupt menopause that may take If I have risk factors does it mean that I am going to get osteoporosis? Osteoporosis - Risk Factors Risk factors you can't change:. Being female; Being Caucasian or Asian; Having a small body build; Having delayed puberty or early menopause Menopause and Osteoporosis Early menopause (before age 45) and any prolonged periods in which hormone levels Heredity is one of the most important risk factors for osteoporosis. Fort Wayne Radiology - Indiana's premiere radiology service provider Risk Factors of Osteoporosis. In the years following menopause, women will naturally experience bone loss because of a decrease in estrogen. U-M study suggests vitamin K deficiency as an osteoporosis risk factor UM study suggests vitamin K deficiency as an osteoporosis risk factor. even before any bone loss that could be attributed to menopause can be measured. EVISTA® (raloxifene HCl): Osteoporosis Risk Factors Risk factors that increase the likelihood of developing osteoporosis and steps to In a study of women past menopause who were at high risk for heart Who is at Risk for Osteoporosis: Osteoporosis Risk Factors Risk factors for osteoporosis can include family history and lifestyle choices. Normal menopause alone increases a womanâ™s risk of osteoporosis. Osteoporosis Risk Factors - Osteoporosis Health Information - NY Menopause. Within 5 years after menopause, the risk for fracture increases Being underweight is a risk factor for osteoporosis in men as well as women. Imaginis - Risk Factors and Symptoms of Osteoporosis The risk factors for osteoporosis are divided into two categories: those that In addition, women who smoke usually experience menopause one to one and a NOF Osteoporosis Prevention - Risk Factors for Osteoporosis The first step in prevention is to determine whether you are at risk, since not everyone is. There are several risk factors for osteoporosis. Osteoporosis: Risk factors - MayoClinic.com For example, you have a lower risk if you have a late menopause or you began For men, alcoholism is one of the leading risk factors for osteoporosis. Osteoporosis Symptoms, Treatment, Information, Risk Factors What are risk factors for developing and causes of osteoporosis? can ease the symptoms of menopause and protect against osteoporosis. |
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