Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Menopause Symptoms, Treatments and Stages of Menopause- BWH What is menopause? Learn about the early symptoms of menopause such as hot flashes or the will atrophy within a year and bleeding will no longer occur. Serious Menopause Symptoms - Which Menopause Symptoms are Dangerous Some symptoms of menopause are urgent and may require medical attention. Look here for information on serious menopause symptoms like heavy bleeding, Menopause Symptoms - Do I Have It? Menopause Symptoms. The primary symptom of Menopause is the cessation of your bleeding as well as heavy bleeding in the years surrounding menopause. Menopause - Symptoms, Diagnosis, Treatment of Menopause - NY Times The symptoms of menopause are caused by changes in estrogen and but because postmenopausal bleeding may also be an early indication of other problems, Menopause and Perimenopause - Yahoo! Health Birth control pills (estrogen and progestin) regulate menstrual bleeding and can relieve symptoms until menopause. Birth control pills are not used after 34 Menopause Symptoms - all about each menopausal symptom. 34 Menopause Symptoms 30. Gum Problems, Increased Bleeding: The most common gum problem is bleeding, and it's a sign of inflamed gums, or what dentists call Menopause Symptoms, What is it? When does it happen? Power Surge Additional Reading: The 34 Signs/Symptoms of Menopause. during perimenopause, but not all changes in bleeding are from perimenopause or menopause. Menopause Symptoms Treatment Center (Sponsored) Your experience with menopausal symptoms is as unique as your own body. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus InteliHealth: Some women don't have any symptoms during menopause or only have a few symptoms. bleeding, but it is not routinely recommended as a test for menopause. Menopause Center - Doctors who treat menopause symptoms & provide The most common of menopause symptoms. A feeling of heat sweeps over the upper irregular bleeding in their menstrual cycle can be a menopause symptom or Bleeding After Menopause - Bleeding After Menopause Symptoms Learn about Bleeding After Menopause, including Bleeding After Menopause symptoms and Bleeding After Menopause Treatment Information. MedlinePlus Medical Encyclopedia: Menopause The symptoms of menopause are caused by changes in estrogen and progesterone levels. and sometimes this will cause postmenopausal bleeding. Treatment of Constant Vaginal Bleeding Close to Menopause - I01 Woman's Diagnostic Cyber Article about treatment of constant vaginal bleeding close to menopause, concern about prolapse symptoms and consideration of Menopause Symptoms and Signs The symptoms of the menopause transition can be divided into early and late onset symptoms. Early symptoms include irregular vaginal bleeding, hot flashes, Perimenopause Symptoms - Pycnogenol and Black Cohosh Information Find out the difference between menopause symptoms and perimenopause symptoms. but not all changes in bleeding are from perimenopause or menopause. Menopause - Signs and Symptoms - womenshealthchannel Signs and symptoms of menopause, such as hot flashes, along with health Women who experience heavy bleeding (usually with clots), periods that come more Perimenopausal and menopausal bleeding PERIMENOPAUSAL AND MENOPAUSAL BLEEDING: Dr. Indman explains what's normal, rapid diagnosis, Other symptoms of menopause include flashes, mood changes, Menopause symptoms, diagnosis, and treatment on MedicineNet.com What are the symptoms of menopause? Irregular vaginal bleeding; Hot flashes & night sweats; Emotional and cognitive symptoms; Vaginal symptoms The menopause Many women experience symptoms of the menopause and irregular periods for Heavy menstrual bleeding is the most common reason for having a hysterectomy. |
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