Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Early menopause symptoms: irregular periods - Early Menopause Remedy Rare or skipped periods usually mean that your ovaries continue declining. But generally, when you come closer to menopause your periods become less Menopause symptoms, diagnosis, and treatment on MedicineNet.com After six years, many of the women were experiencing hot flashes and irregular menstrual periods, two signs of approaching menopause. BBC - Health - Ask the doctor - Post-menopausal bleeding While it could simply be that you're still having a few periods, there are more worrying reasons for bleeding after the menopause which need to be ruled out The menopause The menopause, also called the change of life, is defined as the end of the last menstrual period. In Western women it occurs on average at 51 years, Menopause: What to Expect When Your Body is Changing Menopause is the time in a woman's life when her periods stop and she can't have children anymore. This happens because as a woman ages, her ovaries stop Menopause information - menopause periods, time, age Normal menopause occurs at any time from age 41 to 59. Most premenopausal women experience changes in their menstrual cycle. BMJ BestTreatments :: Conditions :: Menopause :: Irregular periods You can get irregular periods at any time, but they may be a sign that the menopause is approaching. Your menstrual cycle may get shorter or longer. Menopause: Period after 16 months It s not that strange to get a period out of the blue after that much time. If there s any pain associated with it, Id go have your doctor check youout. Dark brownish period during menopause >> Medical Questions, Weight I am 46 years old and am in the middle of menopause. I miss months without having periods, however, the last two were very painful. Menopause Menopause is the medical term used for the last menstrual period a woman will ever have. However, the term is more often used to describe the years leading heavy periods and menopause At 46, heavy periods could mark the start of menopausal changes. MENOPAUSE: Common Problems and Their Remedies According to medical expert Dr. Leon Speroff, "the menopause should and can mark the beginning of a new and promising period of life, relatively free from Menopause 101 - DrDonnica.com - The First Name in Women's Health "Perimenopause" is the 2-10 year time period preceding menopause; it is this period we are now learning more about. "Premature menopause" is defined as Imaginis - Menopause Before menstruation stops completely at menopause, most women will go through pre-menopause and peri-menopause. During pre-menopause, menstrual periods Irregular Menstrual Periods in Perimenopause and Menopause Irregular periods are a common symptom of perimenopause, the time before menopause itself. You may experience a change in the menstrual cycle, MENOPAUSE Menopause is the time in a woman's life when her period stops. It is a normal change in a woman's body. A woman has reached menopause when she has not had a Perimenopausal and menopausal bleeding Menopause is the time in a woman's life when the ovaries stop producing estrogen. Menopause is usually recognized by the cessation of menstrual periods. Learn more about prolonged and heavy perimenopausal bleeding - I01 Periods & Menopause · Uterine Bleeding however they are more common after age 40 and especially in the 2-4 years before menopause. Menopause - Frequently asked questions The formal definition of menopause is the last menstrual period. But most will go through a phase of erratic periods before they reach menopause. |
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