Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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8 days late for my periodpregnant? - Yahoo! UK & Ireland Answers I was really late this month too and i thought i was pregnant I took a test and it Peri-menopause is the period of time where you are transitioning from The Woman's Group - Pregnancy & Menopause Information The most common sign of pregnancy in women is a missed period. . Menopause refers to the date of a woman's last period and usually occurs between the 44 yr. old-Missed period last 2 monthsplease give opinion View Full Version : 44 yr. old-Missed period last 2 monthsplease give opinion . My doc. said that I probably was in pre-menopause the last few years. Late Period age 49 Pregnancy or Menopause? >> Medical Questions I am 49 I had only one pregnancy 30 years ago. After that one, I had never been pregnant again. This last year I started to have irregular period, 10 Reasons Your Period is Late - What to do when you have a missed Peri-menopause is the period of time where you are transitioning from reproductive age to a Yes, your missed period might be because you're pregnant! Women`s Health: missed period and not pregnant There are many possible causes of premature menopause. Subject: missed period and not pregnant Question I have missed a period for almost 2 months this ObGyn/Pregnancy issues: missed period, negative hpt You took the last two tests late enough after a missed period that they should have picked up the hCG if you were pregnant - especially if you used missed period and 3 negative pregnancy tests, Menopause, pregnant Community members of MedHelp provide help, support, guidance and discussion around the topic of missed period and 3 negative pregnancy tests, Menopause, Missed period, HPT is negative, is this menopause? - Menopause Missed period, HPT is negative, is this menopause? 03/17/06 by MrsCoco (last period was Feb 7.) I took a home pregnancyAdolescent pregnancy Missed periods - Pregnancy symptoms - Revolution Health Problems with pregnancy, such as an ectopic pregnancy, also can cause a missed period. This is especially true if you have had a tubal ligation. WOMENS-HEALTH Messages for October, 2002: missed period not pregnant missed period not pregnant. From: Calise (anonymous@obgyn.net) thread subject author ; Next message: Curious: "Re: Pubic HAir Loss in Menopause" Sore breasts and sore nipples - post-ovulation, pregnant There are 2 main causes of sore nipples/breasts before menopause: although pregnancy is the commonest cause of a missed period, there are other causes menopause missed period Pregnancy is no longer possible and the woman no longer menstruates. menopause missed period - The good news is that the herbal remedies are almost 100 Breast tenderness during missed period but not pregnant Learn all about Breast tenderness during missed period but not pregnant So that you know, probably all women will have breast tenderness at some point in Negative Pregnancy Test and Missed Period Missed Period with Negative Pregnancy Test? Find out some Reasons Why. premature menopause is a theoretical explanation for missed periods. Menopause Forum - Late Period Menopause Forum - Late Period, Menopause information, health forums, my period is now 13 days late, i know im not pregnant. i feel like ive had pms now Thyroid & Hormones, Fertility, Menopause Missed period for 71 days now There have been some threads recently WRT pregnancy & thyroid treatment. Menopause & Thyroid Dscns: 84 - Msgs: 627 Thyroid & Hormones, Fertility, Menopause Missed period for 71 days now . Pregnancy & Hyperthyroid 77 discussions, latest 1/11/06 Menopause & Thyroid Dscns: 84 - Msgs: 627 |
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