Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Menopause Symptoms & Safe Menopause Solutions Many women with menopause symptoms go to doctors who prescribe - often incorrectly - some levels of synthetic hormone replacement therapy (HRT), Menopause - Q & A - Better Health Channel. The changing hormone levels during menopause are accompanied by changes to menstruation and other physical and emotional symptoms. Benefits of BioBuilde: Master Amino Acid Pattern (MAP) for During menopause, the adrenal glands begin a new function: producing the body's Other Related Menopause Information:. Hormone Levels · Neurotransmitter Approaching Menopause During true menopause, estrogen and progesterone levels are low and fairly constant. However, during perimenopause, their levels may fluctuate in an HRT-About Progesterone functions, low levels, progestogens in HRT While a woman's estrogen may eventually drop 40-60% at menopause, her progesterone level can drop much lower, upsetting the natural balance (although some Understand estrogen levels and estrogen dominance related to menopause Women want to understand how estrogen levels work and if estrogen dominance is a factor related to menopause. FSH Hormone Tests FSH (Follicle Stimulating Hormone) One-step Threshold Level Menopause test A positive test result indicates FSH hormone levels at or above 25 mIU/ml. HORMONE Tests It's also important if your hormone levels come back normal, but you are experiencing definite symptoms, since you may indeed be beginning menopause, Menopause symptoms, diagnosis, and treatment on MedicineNet.com Are hormone levels or other blood tests helpful in detecting menopause? What are the treatment options for the symptoms of menopause? MedlinePlus Medical Encyclopedia: Menopause Blood and urine tests can be used to measure hormone levels that may indicate when a woman is close to menopause or has already gone through menopause. Introduction: Menopause: Merck Manual Home Edition Rarely, if menopause or perimenopause needs to be confirmed, blood tests are done to measure levels of estrogen and follicle-stimulating hormone (which Hormonal Balance During Menopause When hormone production starts to drop below normal levels in the years leading up to menopause, natural hormones are the best and safest way for women to Menopause - CNN.com Under certain circumstances, your doctor may check your level of follicle-stimulating hormone (FSH) and estrogen (estradiol) with a blood test. As menopause Perimenopause - CNN.com Perimenopause encompasses the years leading up to menopause â” anywhere from two to eight . Some doctors may order tests to check your hormone levels. Womens HealthCare Forum: Menopause Hot flashes: Sometimes referred to as a hot flush or night sweat, these are symptoms of changing hormone levels often considered characteristic of menopause The Menopause Profile To make an informed choice before you do anything, get the information you need about your hormone levels with Great Smokies' Menopause Profile. Here's why. Menopause Online Estrogen is not one hormone, it is the name of a group of hormones. After menopause estradiol levels drop more than estrone so that now estrone is the When Menopause Hormone Levels Stabilize, Symptoms May Abate When Menopause Hormone Levels Stabilize, Symptoms May Abate. Menopause: Self Testing for Menopause The tests themselves cannot correctly determine if you are actually in menopause â“ they merely measure levels of certain hormones. An abnormal hormone level |
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